A stochastic approach to multi-gene expression dynamics
نویسندگان
چکیده
منابع مشابه
A stochastic approach to multi-gene expression dynamics
In the last years, tens of thousands gene expression profiles for cells of several organisms have been monitored. Gene expression is a complex transcriptional process where mRNA molecules are translated into proteins, which control most of the cell functions. In this process, the correlation among genes is crucial to determine the specific functions of genes. Here, we propose a novel multi-dime...
متن کاملA Constructive Approach to Gene Expression Dynamics
The advent of new experimental genomic technologies and the massive increase of DNA sequence information is helping researchers better understand how our genes work. Recently, experiments on mRNA abundance (gene expression) have revealed that gene expression shows a stationary organization described by a power-law distribution (scalefree organization) (i.e., gene expression k decays as k−γ), wh...
متن کاملA Compositional Approach to the Stochastic Dynamics of Gene Networks
We propose a compositional approach to the dynamics of gene regulatory networks based on the stochastic π-calculus, and develop a representation of gene network elements which can be used to build complex circuits in a transparent and efficient way. To demonstrate the power of the approach we apply it to several artificial networks, such as the repressilator and combinatorial gene circuits firs...
متن کاملBackward-stochastic-differential-equation approach to modeling of gene expression.
In this article, we introduce a backward method to model stochastic gene expression and protein-level dynamics. The protein amount is regarded as a diffusion process and is described by a backward stochastic differential equation (BSDE). Unlike many other SDE techniques proposed in the literature, the BSDE method is backward in time; that is, instead of initial conditions it requires the specif...
متن کاملA Discrete Stochastic Approach to Hotel Revenue Management
A linear programming model has been presented for finding an appropriate planning in order to maximize hotel revenue. In this model, a special planning horizon has been considered that includes several busy days of a year. There are several reservation periods that may start a few months earlier. Each period of reservation may have different prices and so result different incomes. Hotel custo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Physics Letters A
سال: 2005
ISSN: 0375-9601
DOI: 10.1016/j.physleta.2005.02.066